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Marathahalli, Bengaluru+91 73377 61236
Neo Fertility Clinic

Fertility Solutions

Intracytoplasmic Sperm Injection (ICSI)

ICSI is a specialised IVF technique that involves injecting a single, healthy sperm directly into an egg, increasing the chances of fertilisation. It is especially beneficial for couples dealing with male factor infertility.

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What ICSI is

ICSI is an advanced form of assisted reproductive technology used alongside IVF to improve fertilisation rates where sperm quality, quantity, or motility is an issue. Unlike conventional IVF, where sperm fertilises the egg naturally in a petri dish, ICSI ensures that a single selected sperm is precisely injected into the egg using a microneedle. This high-precision technique bypasses sperm-related fertility issues.

How it works

The ICSI process, step by step

  1. Hormonal injection being administered near an anatomical model of the ovary

    Ovarian stimulation and monitoring

    The female partner receives hormonal injections to stimulate the ovaries to produce multiple mature eggs. Regular ultrasounds and blood tests monitor follicle development.

  2. Embryologist holding a test tube during egg retrieval

    Egg retrieval procedure

    Once the eggs are mature, they are retrieved through a minor outpatient procedure under sedation. The procedure is painless and takes 10 to 15 minutes.

  3. Single sperm being injected into an egg with a microneedle

    Sperm selection and injection

    A single, healthy sperm is selected and injected directly into each mature egg using a fine microneedle in the lab.

  4. Illustration of a developing baby in the womb

    Embryo development

    Fertilised eggs are monitored for a few days as they develop, and the best-quality embryo is chosen for transfer.

  5. Couple holding a positive pregnancy test

    Embryo transfer and pregnancy test

    The embryo is transferred into the uterus without anesthesia. A pregnancy test follows 10 to 14 days later.

A typical ICSI cycle timeline

  1. 01

    Week 1 to 2

    Ovarian stimulation with hormone injections

  2. 02

    Week 3

    Egg retrieval and sperm collection

  3. 03

    Week 3 to 4

    Fertilisation via ICSI and embryo development in the lab

  4. 04

    Week 4 to 5

    Embryo transfer to the uterus

  5. 05

    Week 6

    Pregnancy test to confirm success

Who benefits

ICSI is best suited to

  • Low sperm count, or oligospermia
  • Poor sperm motility, or asthenozoospermia
  • Abnormal sperm morphology, or teratozoospermia
  • Failed fertilisation in a previous conventional IVF cycle
  • Sperm retrieved surgically via TESA or PESA
ICSI cost in Bangalore
ItemPrice range
ICSI procedure, standalone₹30,000 to ₹50,000
Full IVF and ICSI cycle₹1,80,000 to ₹2,50,000
Surgical sperm retrieval, TESA or PESA₹20,000 to ₹40,000
Frozen embryo transfer, if needed₹50,000 to ₹80,000

Risks include mild bloating or discomfort from ovarian stimulation, a rare risk of Ovarian Hyperstimulation Syndrome, and a chance of multiple pregnancy if more than one embryo is transferred. In rare cases, sperm injection does not result in fertilisation.

Clinical volume

Treated by Dr. Payal Mahapatra

MBBS, DGO, DNB - OBG, Fellowship in Reproductive Medicine. As of August 2026.

18

Years Experience

80k

Patients Treated

6.7k

IUI procedures

3.7k

Fertility surgeries

2k

IVF cycles

1k

Deliveries

FAQ

Questions patients ask

Mild bloating or discomfort due to ovarian stimulation. Ovarian Hyperstimulation Syndrome, a rare but treatable side effect of hormone medications. A chance of multiple pregnancy if more than one embryo is transferred. In rare cases, sperm injection does not result in fertilisation.

Discuss ICSI with a specialist

Book a consultation to find out whether ICSI is needed alongside your IVF cycle, based on semen analysis results.

Monday to Sunday, 09:30 to 18:30

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